MolNFT v1 · #49992 · protein

Crystal structure of the two mbt repeats from sex-comb on midleg (scm)

2R57 · Polycomb protein scm: “Crystal structure of the two mbt repeats from sex-comb on midleg (scm)”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #49992 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2R57
Type: protein
Length: 210 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polycomb protein scm
UniProt: Q9VHA0
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polycomb protein scm	protein	210	16% helix, 30% strand	Q9VHA0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	70	0.34	0.76	16	empty

Compared structures

2R57 · Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) · the same entry in another collection · chain A against A, TM-score 1.00
Q9VHA0 · AlphaFold monomer V2.0 prediction for polycomb protein scm (Q9VHA0) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9VHA0
Elsewhere: RCSB PDB 2R57 · PDBe 2R57 · UniProt Q9VHA0

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