MolNFT v1 · #49666 · protein
A role of the lowe syndrome protein ocrl in early steps of the endocytic pathway
2QV2 · Inositol polyphosphate 5-phosphatase ocrl-1: “A role of the lowe syndrome protein ocrl in early steps of the endocytic pathway”. X-ray diffraction, 1 pocket (best druggability 0.59). MolNFT v1 #49666 on GenesisL1: 3D structure…
- PDB
- 2QV2
- Type
- protein
- Length
- 305 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inositol polyphosphate 5-phosphatase ocrl-1
- EC
- 3.1.3.36
- UniProt
- Q01968
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inositol polyphosphate 5-phosphatase ocrl-1 (EC 3.1.3.36) | protein | 305 | 40% helix, 10% strand | Q01968 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 180 | 0.59 | 0.81 | 30 | empty |
Compared structures
- 2QV2 · A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway · the same entry in another collection · chain A against A, TM-score 1.00
- Q01968 · AlphaFold monomer V2.0 prediction for inositol polyphosphate 5-phosphatase ocrl (Q01968) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01968
- Elsewhere: RCSB PDB 2QV2 · PDBe 2QV2 · UniProt Q01968
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