MolNFT v1 · #49607 · protein
Crystal structure of novel immune-type receptor 11 extracellular fragment mutant N30D
2QTE: “Crystal structure of novel immune-type receptor 11 extracellular fragment mutant N30D”. X-ray diffraction, 5 pockets (best druggability 0.78). MolNFT v1 #49607 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2QTE
- Type
- protein
- Length
- 436 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Novel immune-type receptor 11
- UniProt
- Q8UWK4
- Pockets
- 5 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Novel immune-type receptor 11 | protein | 109 | 6% helix, 51% strand | Q8UWK4 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 614 | 0.78 | 0.84 | 69 | empty |
| 2 | 82 | 0.37 | 0.76 | 19 | empty |
| 3 | 50 | 0.36 | 0.80 | 13 | empty |
| 4 | 84 | 0.34 | 0.75 | 20 | empty |
| 5 | 52 | 0.29 | 0.76 | 14 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1329 Ų buried · 13 hydrogen bonds · protein-protein
- C–D · 1304 Ų buried · 15 hydrogen bonds · protein-protein
- B–D · 360 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 344 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 291 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 2QTE · Crystal Structure of Novel Immune-Type Receptor 11 Extracellular Fragment Mutant N30D · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8UWK4
- Elsewhere: RCSB PDB 2QTE · PDBe 2QTE · UniProt Q8UWK4
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