MolNFT v1 · #49580 · protein

Crystal structure of a luxr family DNA-binding response regulator from silicibacter pomeroyi

2QSJ · DNA-binding response regulator, luxr family: “Crystal structure of a luxr family DNA-binding response regulator from silicibacter pomeroyi”. X-ray diffraction, 3 pockets (best druggability 0.48). MolNFT v1 #49580 on GenesisL1: 3D…

PDB: 2QSJ
Type: protein
Length: 242 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA-binding response regulator, luxr family
UniProt: Q5LQW4
Pockets: 3 · best druggability 0.48

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-binding response regulator, luxr family	protein	120	47% helix, 19% strand	Q5LQW4
B	DNA-binding response regulator, luxr family	protein	122	43% helix, 23% strand	Q5LQW4

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.48	0.86	16	empty
2	90	0.46	0.80	15	empty
3	87	0.46	0.81	19	empty

Interfaces

1 interface between chains.

A–B · 700 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

2QSJ · Crystal structure of a LuxR family DNA-binding response regulator from Silicibacter… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5LQW4
Elsewhere: RCSB PDB 2QSJ · PDBe 2QSJ · UniProt Q5LQW4

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