MolNFT v1 · #49121 · DNA

B-DNA with 7-deaza-dg modification

2QEG · DNA (5'- D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*(7GU)P*DCP*D…: “B-DNA with 7-deaza-dg modification”. X-ray diffraction, 1 pocket (best druggability 0.27). MolNFT v1 #49121 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2QEG
Type: DNA
Length: 24 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA (5'- D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*(7GU)P*DCP*DG)-3')
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	DNA (5'- D(DCPDGPDCPDGPDAPDAPDTPDTPDCP(7GU)PDCPDG)-3')	dna	12	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.27	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 578 Å² buried · 46 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 2 modified (nucleotide modification).

Compared structures

2QEG · B-DNA with 7-deaza-dG modification · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2QEG · PDBe 2QEG

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