MolNFT v1 · #49015 · protein

Structure of C. crescentus sspb ortholog

2QAZ · Sspb protein: “Structure of C. crescentus sspb ortholog”. X-ray diffraction, 4 pockets (best druggability 0.76). MolNFT v1 #49015 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2QAZ
Type: protein
Length: 464 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sspb protein
UniProt: Q9A6J2
Pockets: 4 · best druggability 0.76

Structure

x-ray diffraction · 3 distinct chains · 25% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sspb protein	protein	116	27% helix, 39% strand	Q9A6J2
B, C	Sspb protein	protein	118	25% helix, 38% strand	Q9A6J2
D	Sspb protein	protein	112	24% helix, 31% strand	Q9A6J2

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	697	0.76	0.81	46	empty
2	73	0.43	0.80	18	empty
3	184	0.43	0.73	24	empty
4	76	0.28	0.72	19	empty

Interfaces

3 interfaces between chains.

A–B · 1014 Å² buried · 6 hydrogen bonds · protein-protein
C–D · 905 Å² buried · 5 hydrogen bonds · protein-protein
B–C · 710 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

2QAZ · Structure of C. crescentus SspB ortholog · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9A6J2
Elsewhere: RCSB PDB 2QAZ · PDBe 2QAZ · UniProt Q9A6J2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.