MolNFT v1 · #48853 · protein
The X-ray crystal structure of molybdopterin synthase from staphylococcus aureus
2Q5W · Molybdopterin-converting factor subunit 2: “The X-ray crystal structure of molybdopterin synthase from staphylococcus aureus”. X-ray diffraction, 1 pocket (best druggability 0.40). MolNFT v1 #48853 on GenesisL1: 3D structure…
- PDB
- 2Q5W
- Type
- protein
- Length
- 214 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Molybdopterin-converting factor subunit 2; Molybdopterin converting factor, subunit 1
- UniProt
- P65401, Q5HDT7
- Pockets
- 1 · best druggability 0.40
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Molybdopterin-converting factor subunit 2 | protein | 137 | 31% helix, 36% strand | P65401 |
| D | Molybdopterin converting factor, subunit 1 | protein | 77 | 27% helix, 29% strand | Q5HDT7 |
Ligands and binding sites
- GOL · Glycerol · additive · chains E, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 97 | 0.40 | 0.77 | 20 | GOL |
Interfaces
1 interface between chains.
- E–D · 986 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 2Q5W · The X-ray Crystal Structure of Molybdopterin Synthase from Staphylococcus aureus · the same entry in another collection · chain E against E, TM-score 1.00
- P65401 · AlphaFold monomer V2.0 prediction for molybdopterin synthase catalytic subunit (P65401) · a predicted model of the same protein · chain E against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P65401
- Every structure of UniProt Q5HDT7
- Elsewhere: RCSB PDB 2Q5W · PDBe 2Q5W · UniProt P65401 · UniProt Q5HDT7
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