MolNFT v1 · #48452 · protein

Crystal structure of the T. brucei enolase complexed with sulphate, identification of a metal binding site IV

2PTW: “Crystal structure of the T. brucei enolase complexed with sulphate, identification of a metal binding site IV”. X-ray diffraction, 2 ligands (ZN, SO4), 2 pockets (best druggability 0.56). MolNFT v1 #48452 on GenesisL1: 3D structure…

PDB: 2PTW
Type: protein
Length: 406 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Enolase
EC: 4.2.1.11
UniProt: Q38BV6
Ligands: ZN, SO4
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Enolase (EC 4.2.1.11)	protein	406	44% helix, 17% strand	Q38BV6

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A
SO4 · Sulfate ion · ion · chains A
EDO · 1,2-ethanediol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	149	0.56	0.82	32	ZN, SO4
2	73	0.33	0.75	22	EDO

Compared structures

2PTW · Crystal Structure of the T. brucei enolase complexed with sulphate, identification of a… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q38BV6
Elsewhere: RCSB PDB 2PTW · PDBe 2PTW · UniProt Q38BV6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.