MolNFT v1 · #48448 · protein
Crystal structure of wild type escherichia COLI adenylosuccinate lyase
2PTS: “Crystal structure of wild type escherichia COLI adenylosuccinate lyase”. X-ray diffraction, 1 pocket (best druggability 0.52). MolNFT v1 #48448 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2PTS
- Type
- protein
- Length
- 447 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenylosuccinate lyase
- EC
- 4.3.2.2
- UniProt
- P0AB89
- Pockets
- 1 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adenylosuccinate lyase (EC 4.3.2.2) | protein | 447 | 64% helix, 5% strand | P0AB89 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.52 | 0.79 | 32 | empty |
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
- 2PTS · Crystal structure of wild type Escherichia coli adenylosuccinate lyase · the same entry in another collection · chain A against A, TM-score 1.00
- P0AB89 · AlphaFold monomer V2.0 prediction for adenylosuccinate lyase (P0AB89) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AB89
- Elsewhere: RCSB PDB 2PTS · PDBe 2PTS · UniProt P0AB89
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