MolNFT v1 · #48400 · protein
Structure and metal binding properties of znua, a periplasmic zinc transporter from escherichia COLI
2PS3 · High-affinity zinc uptake system protein znua: “Structure and metal binding properties of znua, a periplasmic zinc transporter from escherichia COLI”. X-ray diffraction, 2 pockets (best druggability 0.61). MolNFT v1 #48400 on…
- PDB
- 2PS3
- Type
- protein
- Length
- 529 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- High-affinity zinc uptake system protein znua
- UniProt
- P39172
- Pockets
- 2 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | High-affinity zinc uptake system protein znua | protein | 265 | 49% helix, 12% strand | P39172 |
| B | High-affinity zinc uptake system protein znua | protein | 264 | 47% helix, 11% strand | P39172 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 486 | 0.61 | 0.75 | 60 | empty |
| 2 | 99 | 0.34 | 0.74 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 512 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2PS3 · Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from… · the same entry in another collection · chain B against B, TM-score 1.00
- P39172 · AlphaFold monomer V2.0 prediction for high-affinity zinc uptake system protein znua… · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39172
- Elsewhere: RCSB PDB 2PS3 · PDBe 2PS3 · UniProt P39172
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