MolNFT v1 · #48179 · protein
Phosphatidylinositol-specific phospholipase C from listeria monocytogenes
2PLC: “Phosphatidylinositol-specific phospholipase C from listeria monocytogenes”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #48179 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2PLC
- Type
- protein
- Length
- 274 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylinositol-specific phospholipase C
- EC
- 3.1.4.10
- UniProt
- P34024
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol-specific phospholipase C (EC 3.1.4.10) | protein | 274 | 36% helix, 23% strand | P34024 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.36 | 0.76 | 19 | empty |
Compared structures
- 2PLC · Phosphatidylinositol-specific phospholipase C from listeria monocytogenes · the same entry in another collection · chain A against A, TM-score 1.00
- P34024 · AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol phosphodiesterase (P34024) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P34024
- Elsewhere: RCSB PDB 2PLC · PDBe 2PLC · UniProt P34024
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.