MolNFT v1 · #48127 · protein
Crystal structure of Q88U62_LACPL from lactobacillus plantarum. northeast structural genomics target LPR71
2PJQ · Uncharacterized protein LP_2664: “Crystal structure of Q88U62_LACPL from lactobacillus plantarum. northeast structural genomics target LPR71”. X-ray diffraction, 11 pockets (best druggability 0.78). MolNFT v1 #48127 on GenesisL1: 3D…
- PDB
- 2PJQ
- Type
- protein
- Length
- 833 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein LP_2664
- UniProt
- Q88U62
- Pockets
- 11 · best druggability 0.78
Structure
x-ray diffraction · 4 distinct chains · 65% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein LP_2664 | protein | 206 | 67% helix, 0% strand | Q88U62 |
| B | Uncharacterized protein LP_2664 | protein | 212 | 67% helix, 1% strand | Q88U62 |
| C | Uncharacterized protein LP_2664 | protein | 212 | 64% helix, 0% strand | Q88U62 |
| D | Uncharacterized protein LP_2664 | protein | 203 | 63% helix, 0% strand | Q88U62 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 618 | 0.78 | 0.84 | 50 | empty |
| 2 | 808 | 0.78 | 0.81 | 60 | empty |
| 3 | 677 | 0.76 | 0.82 | 68 | empty |
| 4 | 886 | 0.75 | 0.79 | 93 | empty |
| 5 | 538 | 0.75 | 0.83 | 61 | empty |
Interfaces
5 interfaces between chains.
- B–C · 1496 Ų buried · 15 hydrogen bonds · protein-protein
- B–D · 368 Ų buried · 3 hydrogen bonds · protein-protein
- A–B · 301 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 226 Ų buried · 0 hydrogen bonds · protein-protein
- C–D · 48 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 22 modified (engineered).
Compared structures
- 2PJQ · Crystal structure of Q88U62_LACPL from Lactobacillus plantarum. Northeast Structural… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q88U62
- Elsewhere: RCSB PDB 2PJQ · PDBe 2PJQ · UniProt Q88U62
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.