MolNFT v1 · #48123 · protein
E. COLI lytic transglycosylase mlta-D308A in apo-1 form
2PJJ · Membrane-bound lytic murein transglycosylase a: “E. COLI lytic transglycosylase mlta-D308A in apo-1 form”. X-ray diffraction, 4 pockets (best druggability 0.67). MolNFT v1 #48123 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 2PJJ
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Membrane-bound lytic murein transglycosylase a
- EC
- 3.2.1.-
- UniProt
- P0A935
- Pockets
- 4 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Membrane-bound lytic murein transglycosylase a (EC 3.2.1.-) | protein | 335 | 28% helix, 30% strand | P0A935 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 471 | 0.67 | 0.79 | 59 | empty |
| 2 | 88 | 0.61 | 0.89 | 19 | empty |
| 3 | 71 | 0.50 | 0.84 | 21 | empty |
| 4 | 158 | 0.46 | 0.76 | 30 | empty |
Compared structures
- 2PJJ · E. coli lytic transglycosylase MltA-D308A in apo-1 form · the same entry in another collection · chain A against A, TM-score 1.00
- P0A935 · AlphaFold monomer V2.0 prediction for membrane-bound lytic murein transglycosylase a… · a predicted model of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A935
- Elsewhere: RCSB PDB 2PJJ · PDBe 2PJJ · UniProt P0A935
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