MolNFT v1 · #48004 · protein
S. cerevisiae EXO70 with additional residues to 2.1 angrstrom resolution
2PFV · Exocyst complex component EXO70: “S. cerevisiae EXO70 with additional residues to 2.1 angrstrom resolution”. X-ray diffraction, 3 pockets (best druggability 0.57). MolNFT v1 #48004 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2PFV
- Type
- protein
- Length
- 549 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Exocyst complex component EXO70
- UniProt
- P19658
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Exocyst complex component EXO70 | protein | 549 | 72% helix, 0% strand | P19658 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.57 | 0.86 | 20 | empty |
| 2 | 50 | 0.33 | 0.78 | 16 | empty |
| 3 | 52 | 0.33 | 0.77 | 14 | empty |
Compared structures
- 2PFV · S. cerevisiae Exo70 with additional residues to 2.1 Angrstrom resolution · the same entry in another collection · chain A against A, TM-score 1.00
- P19658 · AlphaFold monomer V2.0 prediction for exocyst complex component EXO70 (P19658) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19658
- Elsewhere: RCSB PDB 2PFV · PDBe 2PFV · UniProt P19658
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