MolNFT v1 · #47824 · protein

Crystal structure of human ribosomal protein L10 core domain

2PA2 · 60S ribosomal protein L10: “Crystal structure of human ribosomal protein L10 core domain”. X-ray diffraction, 1 ligand (K), 1 pocket (best druggability 0.75). MolNFT v1 #47824 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2PA2
Type: protein
Length: 216 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 60S ribosomal protein L10
UniProt: P27635
Ligands: K
Pockets: 1 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	60S ribosomal protein L10	protein	108	33% helix, 32% strand	P27635

Ligands and binding sites

K · Potassium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	433	0.75	0.84	54	empty

Interfaces

1 interface between chains.

A–B · 1041 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

2PA2 · Crystal structure of human Ribosomal protein L10 core domain · the same entry in another collection · chain A against A, TM-score 1.00
P27635 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (P27635) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27635
Elsewhere: RCSB PDB 2PA2 · PDBe 2PA2 · UniProt P27635

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