MolNFT v1 · #4775 · protein
Structure of the imipenem-hydrolyzing beta-lactamase sme-1
1DY6 · Carbapenem-hydrolysing beta-lactamase sme-1: “Structure of the imipenem-hydrolyzing beta-lactamase sme-1”. X-ray diffraction, 2 pockets (best druggability 0.31). MolNFT v1 #4775 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1DY6
- Type
- protein
- Length
- 534 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbapenem-hydrolysing beta-lactamase sme-1
- EC
- 3.5.2.6
- UniProt
- Q54488
- Pockets
- 2 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Carbapenem-hydrolysing beta-lactamase sme-1 (EC 3.5.2.6) | protein | 267 | 43% helix, 17% strand | Q54488 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 78 | 0.31 | 0.74 | 17 | empty |
| 2 | 59 | 0.27 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1DY6 · Structure of the imipenem-hydrolyzing beta-lactamase SME-1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q54488
- Elsewhere: RCSB PDB 1DY6 · PDBe 1DY6 · UniProt Q54488
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