MolNFT v1 · #47491 · protein

Structure of the N-terminally truncated pas domain of signal transduction histidine kinase from nostoc punctiforme pcc 73102 with homology to the H-NOXA/H-noba domain of the soluble guanylyl cyclase

2P08: “Structure of the N-terminally truncated pas domain of signal transduction histidine kinase from nostoc…”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.31). MolNFT v1 #47491 on GenesisL1: 3D structure, binding…

PDB: 2P08
Type: protein
Length: 217 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Signal transduction histidine kinase
EC: 2.7.3.-
Ligands: SO4
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 2 distinct chains · 18% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Signal transduction histidine kinase (EC 2.7.3.-)	protein	107	20% helix, 34% strand	—
B	Signal transduction histidine kinase (EC 2.7.3.-)	protein	110	16% helix, 32% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	74	0.31	0.74	20	empty

Interfaces

1 interface between chains.

A–B · 937 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

2P08 · Structure of the N-terminally truncated PAS domain of signal transduction histidine… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2P08 · PDBe 2P08

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