MolNFT v1 · #47444 · protein
Crystal structure of UPF0341 protein (yhiq) from shigella flexneri in complex with S-adenosyl homocysteine, northeast structural genomics target SFR275
2OYR · UPF0341 protein yhiq: “Crystal structure of UPF0341 protein (yhiq) from shigella flexneri in complex with S-adenosyl homocysteine…”. X-ray diffraction, 1 ligand (SAH), 2 pockets (best druggability 0.70). MolNFT v1 #47444 on…
- PDB
- 2OYR
- Type
- protein
- Length
- 245 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UPF0341 protein yhiq
- UniProt
- Q7UAV7
- Ligands
- SAH
- Pockets
- 2 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | UPF0341 protein yhiq | protein | 245 | 36% helix, 23% strand | Q7UAV7 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 272 | 0.70 | 0.85 | 45 | SAH |
| 2 | 123 | 0.46 | 0.78 | 23 | empty |
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2OYR · Crystal Structure of UPF0341 Protein (yhiQ) from Shigella flexneri in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q7UAV7 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase J… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7UAV7
- Elsewhere: RCSB PDB 2OYR · PDBe 2OYR · UniProt Q7UAV7
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