MolNFT v1 · #47125 · protein
Crystal structure of ywhb- homologue of 4-oxalocrotonate tautomerase
2OP8 · Probable tautomerase ywhb: “Crystal structure of ywhb- homologue of 4-oxalocrotonate tautomerase”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #47125 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2OP8
- Type
- protein
- Length
- 122 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable tautomerase ywhb
- EC
- 5.3.2.-
- UniProt
- P70994
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Probable tautomerase ywhb (EC 5.3.2.-) | protein | 61 | 46% helix, 30% strand | P70994 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.31 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 906 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 2OP8 · Crystal Structure of YwhB- Homologue of 4-Oxalocrotonate Tautomerase · the same entry in another collection · chain A against A, TM-score 1.00
- P70994 · AlphaFold monomer V2.0 prediction for 2-hydroxymuconate tautomerase (P70994) · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P70994
- Elsewhere: RCSB PDB 2OP8 · PDBe 2OP8 · UniProt P70994
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