MolNFT v1 · #47097 · protein

Crystal structure of hat domain of murine cstf-77

2OOE · Cleavage stimulation factor 77 kda subunit: “Crystal structure of hat domain of murine cstf-77”. X-ray diffraction, 4 pockets (best druggability 0.63). MolNFT v1 #47097 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2OOE
Type: protein
Length: 528 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cleavage stimulation factor 77 kda subunit
UniProt: Q99LI7
Pockets: 4 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cleavage stimulation factor 77 kda subunit	protein	528	72% helix, 0% strand	Q99LI7

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	393	0.63	0.78	48	empty
2	184	0.50	0.77	24	empty
3	69	0.34	0.76	16	empty
4	52	0.29	0.76	14	empty

Compared structures

2OOE · Crystal structure of HAT domain of murine CstF-77 · the same entry in another collection · chain A against A, TM-score 1.00
Q99LI7 · AlphaFold monomer V2.0 prediction for cleavage stimulation factor subunit 3 (Q99LI7) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99LI7
Elsewhere: RCSB PDB 2OOE · PDBe 2OOE · UniProt Q99LI7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.