MolNFT v1 · #47038 · protein
Crystal structure of E. COLI pseudouridine synthase rlue
2OML · Ribosomal large subunit pseudouridine synthase E: “Crystal structure of E. COLI pseudouridine synthase rlue”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.58). MolNFT v1 #47038 on GenesisL1: 3D structure, binding…
- PDB
- 2OML
- Type
- protein
- Length
- 181 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosomal large subunit pseudouridine synthase E
- EC
- 5.4.99.-
- UniProt
- P75966
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosomal large subunit pseudouridine synthase E (EC 5.4.99.-) | protein | 181 | 15% helix, 31% strand | P75966 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.58 | 0.83 | 29 | SO4 |
Compared structures
- 2OML · crystal structure of E. coli pseudouridine synthase RluE · the same entry in another collection · chain A against A, TM-score 1.00
- P75966 · AlphaFold monomer V2.0 prediction for ribosomal large subunit pseudouridine synthase E… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P75966
- Elsewhere: RCSB PDB 2OML · PDBe 2OML · UniProt P75966
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.