MolNFT v1 · #46942 · protein

Crystal structure of alix V domain

2OJQ · Programmed cell death 6-interacting protein: “Crystal structure of alix V domain”. X-ray diffraction, 4 pockets (best druggability 0.65). MolNFT v1 #46942 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2OJQ
Type: protein
Length: 343 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Programmed cell death 6-interacting protein
UniProt: Q8WUM4
Pockets: 4 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Programmed cell death 6-interacting protein	protein	343	79% helix, 0% strand	Q8WUM4

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.65	0.95	21	empty
2	195	0.64	0.84	27	empty
3	220	0.51	0.76	30	empty
4	54	0.36	0.79	15	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

2OJQ · Crystal structure of Alix V domain · the same entry in another collection · chain A against A, TM-score 1.00
Q8WUM4 · AlphaFold monomer V2.0 prediction for programmed cell death 6-interacting protein (Q8WUM4) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WUM4
Elsewhere: RCSB PDB 2OJQ · PDBe 2OJQ · UniProt Q8WUM4

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