MolNFT v1 · #46851 · protein
Structure of ABC type zinc transporter from E. COLI
2OGW · High-affinity zinc uptake system protein znua precursor: “Structure of ABC type zinc transporter from E. COLI”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.60). MolNFT v1 #46851 on GenesisL1: 3D structure…
- PDB
- 2OGW
- Type
- protein
- Length
- 520 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- High-affinity zinc uptake system protein znua precursor
- UniProt
- P39172
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | High-affinity zinc uptake system protein znua precursor | protein | 260 | 52% helix, 12% strand | P39172 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 416 | 0.60 | 0.76 | 53 | empty |
| 2 | 59 | 0.27 | 0.74 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 330 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified, 2 disulfide (engineered, disulfide).
Compared structures
- 2OGW · Structure of ABC type zinc transporter from E. coli · the same entry in another collection · chain A against A, TM-score 1.00
- P39172 · AlphaFold monomer V2.0 prediction for high-affinity zinc uptake system protein znua… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39172
- Elsewhere: RCSB PDB 2OGW · PDBe 2OGW · UniProt P39172
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