MolNFT v1 · #46837 · protein

Solution structure of yeast EIF1

2OGH · Eukaryotic translation initiation factor eif-1: “Solution structure of yeast EIF1”. Solution nmr, 2 pockets (best druggability 0.62). MolNFT v1 #46837 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2OGH
Type: protein
Length: 108 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Eukaryotic translation initiation factor eif-1
UniProt: P32911
Pockets: 2 · best druggability 0.62

Structure

solution nmr · 1 distinct chain · 22% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Eukaryotic translation initiation factor eif-1	protein	108	22% helix, 21% strand	P32911

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.62	0.90	19	empty
2	65	0.31	0.75	14	empty

Compared structures

2OGH · Solution structure of yeast eIF1 · the same entry in another collection · chain A against A, TM-score 1.00
P32911 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor eif-1… · a predicted model of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32911
Elsewhere: RCSB PDB 2OGH · PDBe 2OGH · UniProt P32911

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