MolNFT v1 · #46827 · protein

Crystal structure of asparagine oxygenase in complex with FE(II)

2OG6: “Crystal structure of asparagine oxygenase in complex with FE(II)”. X-ray diffraction, 2 ligands (FE2, CL), 4 pockets (best druggability 0.67). MolNFT v1 #46827 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2OG6
Type: protein
Length: 323 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Asparagine oxygenase
UniProt: Q9Z4Z5
Ligands: FE2, CL
Pockets: 4 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Asparagine oxygenase	protein	323	31% helix, 22% strand	Q9Z4Z5

Ligands and binding sites

FE2 · Fe (II) ion · metal · chains A
CL · Chloride ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	331	0.67	0.81	42	empty
2	94	0.35	0.73	12	empty
3	54	0.33	0.77	17	empty
4	50	0.27	0.74	15	empty

Compared structures

2OG6 · Crystal structure of asparagine oxygenase in complex with Fe(II) · the same entry in another collection · chain A against A, TM-score 1.00
Q9Z4Z5 · AlphaFold monomer V2.0 prediction for L-asparagine oxygenase (Q9Z4Z5) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Z4Z5
Elsewhere: RCSB PDB 2OG6 · PDBe 2OG6 · UniProt Q9Z4Z5

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