MolNFT v1 · #46717 · protein
The structure of a putative 3-dehydroquinate dehydratase from streptococcus pyogenes.
2OCZ: “The structure of a putative 3-dehydroquinate dehydratase from streptococcus pyogenes.”. X-ray diffraction, 1 ligand (MG), 1 pocket (best druggability 0.69). MolNFT v1 #46717 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2OCZ
- Type
- protein
- Length
- 218 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-dehydroquinate dehydratase
- EC
- 4.2.1.10
- UniProt
- P63590
- Ligands
- MG
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-dehydroquinate dehydratase (EC 4.2.1.10) | protein | 218 | 47% helix, 22% strand | P63590 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 275 | 0.69 | 0.84 | 43 | EDO |
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
- 2OCZ · The Structure of a Putative 3-Dehydroquinate Dehydratase from Streptococcus pyogenes. · the same entry in another collection · chain A against A, TM-score 1.00
- P63590 · AlphaFold monomer V2.0 prediction for 3-dehydroquinate dehydratase (P63590) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63590
- Elsewhere: RCSB PDB 2OCZ · PDBe 2OCZ · UniProt P63590
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