MolNFT v1 · #46582 · protein
Crystal structure of a putative 14-3-3 protein from cryptosporidium parvum, CGD7_2470
2O8P · 14-3-3 domain containing protein: “Crystal structure of a putative 14-3-3 protein from cryptosporidium parvum, CGD7_2470”. X-ray diffraction, 2 pockets (best druggability 0.35). MolNFT v1 #46582 on GenesisL1: 3D structure, binding…
- PDB
- 2O8P
- Type
- protein
- Length
- 220 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 14-3-3 domain containing protein
- UniProt
- Q5CYG0
- Pockets
- 2 · best druggability 0.35
Structure
x-ray diffraction · 1 distinct chain · 84% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 14-3-3 domain containing protein | protein | 220 | 84% helix, 0% strand | Q5CYG0 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.35 | 0.74 | 21 | empty |
| 2 | 53 | 0.31 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 2O8P · Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5CYG0
- Elsewhere: RCSB PDB 2O8P · PDBe 2O8P · UniProt Q5CYG0
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