MolNFT v1 · #46393 · RNA

Solution structure of U2 snrna stem I from human, containing modified nucleotides

2O32 · 5'-R(*(PSU)P*CP*UP*CP*(OMG)P*(OMG)P*CP*CP*(PSU)…: “Solution structure of U2 snrna stem I from human, containing modified nucleotides”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #46393 on GenesisL1: 3D structure…

PDB: 2O32
Type: RNA
Length: 20 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'-R(*(PSU)P*CP*UP*CP*(OMG)P*(OMG)P*CP*CP*(PSU)…
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	5'-R((PSU)PCPUPCP(OMG)P(OMG)PCPCP(PSU) PUPUPUP(OMG)PGPCPUPAPAP(OMG)PA)-3'	rna	20	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.32	0.73	15	empty

Modifications

Observed in the structure: 6 modified (nucleotide modification).

Compared structures

2O32 · Solution structure of U2 snRNA stem I from human, containing modified nucleotides · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2O32 · PDBe 2O32

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