MolNFT v1 · #46325 · protein
Mycobacterium tuberculosis epsp synthase after partial products withdrawal
2O15 · 3-phosphoshikimate 1-carboxyvinyltransferase: “Mycobacterium tuberculosis epsp synthase after partial products withdrawal”. X-ray diffraction, 2 ligands (PO4, SO4), 1 pocket (best druggability 0.78). MolNFT v1 #46325 on GenesisL1…
- PDB
- 2O15
- Type
- protein
- Length
- 424 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-phosphoshikimate 1-carboxyvinyltransferase
- EC
- 2.5.1.19
- UniProt
- P22487
- Ligands
- PO4, SO4
- Pockets
- 1 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) | protein | 424 | 37% helix, 22% strand | P22487 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 338 | 0.78 | 0.89 | 55 | PO4 |
Compared structures
- 2O15 · Mycobacterium tuberculosis epsp synthase after partial products withdrawal · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22487
- Elsewhere: RCSB PDB 2O15 · PDBe 2O15 · UniProt P22487
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