MolNFT v1 · #46203 · protein
Crystal structure of a dimetal phosphatase from danio rerio loc 393393
2NXF · Putative dimetal phosphatase: “Crystal structure of a dimetal phosphatase from danio rerio loc 393393”. X-ray diffraction, 2 ligands (ZN, PO4), 2 pockets (best druggability 0.62). MolNFT v1 #46203 on GenesisL1: 3D structure, binding…
- PDB
- 2NXF
- Type
- protein
- Length
- 314 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative dimetal phosphatase
- UniProt
- Q7T291
- Ligands
- ZN, PO4
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative dimetal phosphatase | protein | 314 | 30% helix, 24% strand | Q7T291 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains A
- PO4 · Phosphate ion · ion · chains A
- EOH · Ethanol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 393 | 0.62 | 0.78 | 32 | PO4 |
| 2 | 53 | 0.27 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 3 modified, 1 disulfide (engineered, disulfide).
Compared structures
- 2NXF · Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393 · the same entry in another collection · chain A against A, TM-score 1.00
- Q7T291 · AlphaFold monomer V2.0 prediction for manganese-dependent ADP- RIBOSE/CDP-alcohol… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7T291
- Elsewhere: RCSB PDB 2NXF · PDBe 2NXF · UniProt Q7T291
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