MolNFT v1 · #46102 · protein

Structure of aquifex aeolicus argonuate

2NUB · Argonaute: “Structure of aquifex aeolicus argonuate”. X-ray diffraction, 11 pockets (best druggability 0.72). MolNFT v1 #46102 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2NUB
Type: protein
Length: 690 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Argonaute
UniProt: O67434
Pockets: 11 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Argonaute	protein	690	29% helix, 26% strand	O67434

Pockets

11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	767	0.72	0.78	73	empty
2	446	0.65	0.78	54	empty
3	210	0.52	0.77	25	empty
4	119	0.43	0.76	16	empty
5	65	0.43	0.81	14	empty

Compared structures

2NUB · Structure of Aquifex aeolicus Argonuate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O67434
Elsewhere: RCSB PDB 2NUB · PDBe 2NUB · UniProt O67434

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