MolNFT v1 · #46039 · protein
E. COLI pure H45Q mutant complexed with cair
2NSJ · Phosphoribosylaminoimidazole carboxylase catalytic subunit: “E. COLI pure H45Q mutant complexed with cair”. X-ray diffraction, 1 ligand (C2R), 1 pocket (best druggability 0.32). MolNFT v1 #46039 on GenesisL1: 3D structure, binding…
- PDB
- 2NSJ
- Type
- protein
- Length
- 162 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosylaminoimidazole carboxylase catalytic subunit
- EC
- 4.1.1.21
- UniProt
- P0AG18
- Ligands
- C2R
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) | protein | 162 | 47% helix, 15% strand | P0AG18 |
Ligands and binding sites
- C2R · 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.32 | 0.78 | 14 | C2R |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AG18
- Elsewhere: RCSB PDB 2NSJ · PDBe 2NSJ · UniProt P0AG18
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.