MolNFT v1 · #45981 · protein
MOEA E188Q
2NQU · Molybdopterin biosynthesis protein moea: “MOEA E188Q”. X-ray diffraction, 10 pockets (best druggability 0.76). MolNFT v1 #45981 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2NQU
- Type
- protein
- Length
- 807 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Molybdopterin biosynthesis protein moea
- UniProt
- P12281
- Pockets
- 10 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 21% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Molybdopterin biosynthesis protein moea | protein | 403 | 20% helix, 32% strand | P12281 |
| B | Molybdopterin biosynthesis protein moea | protein | 404 | 22% helix, 31% strand | P12281 |
Ligands and binding sites
- GOL · Glycerol · additive · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 586 | 0.76 | 0.83 | 70 | empty |
| 2 | 1080 | 0.76 | 0.78 | 84 | GOL |
| 3 | 634 | 0.67 | 0.76 | 61 | GOL |
| 4 | 314 | 0.63 | 0.80 | 34 | GOL |
| 5 | 107 | 0.54 | 0.83 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 2322 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12281
- Elsewhere: RCSB PDB 2NQU · PDBe 2NQU · UniProt P12281
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.