MolNFT v1 · #45799 · protein

HIV-1 nef (regulatory factor), NMR, 40 structures

2NEF · Negative factor (F-protein): “HIV-1 nef (regulatory factor), NMR, 40 structures”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #45799 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2NEF
Type: protein
Length: 136 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Negative factor (F-protein)
UniProt: Q70627
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 26% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Negative factor (F-protein)	protein	136	26% helix, 10% strand	Q70627

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	105	0.48	0.79	15	empty

Compared structures

2NEF · HIV-1 nef (regulatory factor), NMR, 40 structures · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q70627
Elsewhere: RCSB PDB 2NEF · PDBe 2NEF · UniProt Q70627

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