MolNFT v1 · #45731 · protein

The solution structure of human gammac-crystallin

2NBR · Gamma-crystallin C: “The solution structure of human gammac-crystallin”. Solution nmr, 1 pocket (best druggability 0.51). MolNFT v1 #45731 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2NBR
Type: protein
Length: 173 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gamma-crystallin C
UniProt: P07315
Pockets: 1 · best druggability 0.51

Structure

solution nmr · 1 distinct chain · 5% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gamma-crystallin C	protein	173	5% helix, 49% strand	P07315

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	124	0.51	0.80	24	empty

Compared structures

2NBR · The Solution Structure of Human gammaC-crystallin · the same entry in another collection · chain A against A, TM-score 1.00
P07315 · AlphaFold monomer V2.0 prediction for gamma-crystallin C (P07315) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07315
Elsewhere: RCSB PDB 2NBR · PDBe 2NBR · UniProt P07315

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