MolNFT v1 · #45728 · protein
Solution structure of the F87M/L110M variant of transthyretin in the monomeric state
2NBO: “Solution structure of the F87M/L110M variant of transthyretin in the monomeric state”. Solution nmr, 2 pockets (best druggability 0.45). MolNFT v1 #45728 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2NBO
- Type
- protein
- Length
- 127 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transthyretin
- UniProt
- P02766
- Pockets
- 2 · best druggability 0.45
Structure
solution nmr · 1 distinct chain · 7% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transthyretin | protein | 127 | 7% helix, 30% strand | P02766 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 116 | 0.45 | 0.78 | 21 | empty |
| 2 | 60 | 0.40 | 0.81 | 21 | empty |
Compared structures
- 2NBO · Solution structure of the F87M/L110M variant of transthyretin in the monomeric state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02766
- Elsewhere: RCSB PDB 2NBO · PDBe 2NBO · UniProt P02766
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