MolNFT v1 · #45716 · protein

NMR structure of the acidic domain of syncrip (24-140)

2NBB · Heterogeneous nuclear ribonucleoprotein Q: “NMR structure of the acidic domain of syncrip (24-140)”. Solution nmr, 1 pocket (best druggability 0.63). MolNFT v1 #45716 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2NBB
Type: protein
Length: 118 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heterogeneous nuclear ribonucleoprotein Q
UniProt: O60506
Pockets: 1 · best druggability 0.63

Structure

solution nmr · 1 distinct chain · 36% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heterogeneous nuclear ribonucleoprotein Q	protein	118	36% helix, 0% strand	O60506

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.63	0.87	25	empty

Compared structures

2NBB · NMR structure of the Acidic domain of SYNCRIP (24-140) · the same entry in another collection · chain A against A, TM-score 1.00
O60506 · AlphaFold monomer V2.0 prediction for heterogeneous nuclear ribonucleoprotein Q (O60506) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60506
Elsewhere: RCSB PDB 2NBB · PDBe 2NBB · UniProt O60506

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.