MolNFT v1 · #45582 · protein + RNA

Solution structure of plasmodium falciparum SR1-RRM1 in complex with acauca RNA

2N7C · Putative splicing factor: “Solution structure of plasmodium falciparum SR1-RRM1 in complex with acauca RNA”. Solution nmr, 1 pocket (best druggability 0.39). MolNFT v1 #45582 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2N7C
Type: protein + RNA
Length: 95 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative splicing factor; RNA_(5'-R(*AP*CP*AP*UP*CP*A)-3')
UniProt: Q8I3T5
Pockets: 1 · best druggability 0.39

Structure

solution nmr · 2 distinct chains · 24% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative splicing factor	protein	89	24% helix, 26% strand	Q8I3T5
B	RNA_(5'-R(APCPAPUPCPA)-3')	rna	6	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.39	0.77	17	empty

Interfaces

1 interface between chains.

A–B · 587 Å² buried · 14 hydrogen bonds · protein-nucleic

Compared structures

2N7C · Solution structure of Plasmodium falciparum SR1-RRM1 in complex with ACAUCA RNA · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8I3T5
Elsewhere: RCSB PDB 2N7C · PDBe 2N7C · UniProt Q8I3T5

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