MolNFT v1 · #45505 · protein
Solution structure of ovis aries prp
2N53 · Major prion protein: “Solution structure of ovis aries prp”. Solution nmr, 2 pockets (best druggability 0.42). MolNFT v1 #45505 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2N53
- Type
- protein
- Length
- 143 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major prion protein
- UniProt
- Q712V9
- Pockets
- 2 · best druggability 0.42
Structure
solution nmr · 1 distinct chain · 45% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major prion protein | protein | 143 | 45% helix, 0% strand | Q712V9 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.42 | 0.76 | 18 | empty |
| 2 | 73 | 0.35 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2N53 · Solution structure of ovis aries prp · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q712V9
- Elsewhere: RCSB PDB 2N53 · PDBe 2N53 · UniProt Q712V9
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