MolNFT v1 · #45314 · protein

Solution NMR structure of salmonella typhimurium transcriptional regulator protein crl

2MZ8 · Sigma factor-binding protein crl: “Solution NMR structure of salmonella typhimurium transcriptional regulator protein crl”. Solution nmr, 3 pockets (best druggability 0.49). MolNFT v1 #45314 on GenesisL1: 3D structure, binding sites…

PDB: 2MZ8
Type: protein
Length: 133 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sigma factor-binding protein crl
UniProt: Q7CR52
Pockets: 3 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 27% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sigma factor-binding protein crl	protein	133	27% helix, 17% strand	Q7CR52

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.49	0.81	21	empty
2	100	0.43	0.78	15	empty
3	59	0.42	0.82	22	empty

Compared structures

2MZ8 · Solution NMR structure of Salmonella Typhimurium transcriptional regulator protein Crl · the same entry in another collection · chain A against A, TM-score 1.00
Q7CR52 · AlphaFold monomer V2.0 prediction for sigma factor-binding protein crl (Q7CR52) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7CR52
Elsewhere: RCSB PDB 2MZ8 · PDBe 2MZ8 · UniProt Q7CR52

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