MolNFT v1 · #45292 · protein

Solution structure of a bacterial chaperone

2MYJ · Acid stress chaperone hdeb: “Solution structure of a bacterial chaperone”. Solution nmr, 1 pocket (best druggability 0.57). MolNFT v1 #45292 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2MYJ
Type: protein
Length: 158 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acid stress chaperone hdeb
UniProt: P0AET2
Pockets: 1 · best druggability 0.57

Structure

solution nmr · 1 distinct chain · 49% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Acid stress chaperone hdeb	protein	79	49% helix, 3% strand	P0AET2

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	122	0.57	0.84	30	empty

Interfaces

1 interface between chains.

A–B · 1206 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2MYJ · Solution structure of a bacterial chaperone · the same entry in another collection · chain A against A, TM-score 1.00
P0AET2 · AlphaFold monomer V2.0 prediction for acid stress chaperone hdeb (P0AET2) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AET2
Elsewhere: RCSB PDB 2MYJ · PDBe 2MYJ · UniProt P0AET2

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