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MolNFT v1 · #45273 · protein + RNA

Solution structure of hnrnp C rrm in complex with 5'-auuuuuc-3' RNA

2MXY · Heterogeneous nuclear ribonucleoproteins C1/C2: “Solution structure of hnrnp C rrm in complex with 5'-auuuuuc-3' RNA”. Solution nmr. MolNFT v1 #45273 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2MXY
Type
protein + RNA
Length
112 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Heterogeneous nuclear ribonucleoproteins C1/C2; 5'-R(*AP*UP*UP*UP*UP*UP*C)-3'
UniProt
P07910

Structure

solution nmr · 2 distinct chains · 14% helix, 24% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHeterogeneous nuclear ribonucleoproteins C1/C2protein10514% helix, 24% strandP07910
B5'-R(*AP*UP*UP*UP*UP*UP*C)-3'rna7——

Interfaces

1 interface between chains.

  • A–B · 1029 Ų buried · 20 hydrogen bonds · protein-nucleic

Compared structures

  • 2MXY · Solution structure of hnRNP C RRM in complex with 5'-AUUUUUC-3' RNA · the same entry in another collection · chain A against A, TM-score 1.00
  • P07910 · AlphaFold monomer V2.0 prediction for heterogeneous nuclear ribonucleoproteins C1/C2… · a predicted model of the same protein · chain A against A, TM-score 0.83

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