MolNFT v1 · #45248 · protein

Solution structure of the internal eh domain of gamma-synergin

2MX7 · Synergin gamma: “Solution structure of the internal eh domain of gamma-synergin”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #45248 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2MX7
Type: protein
Length: 112 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Synergin gamma
UniProt: Q9UMZ2
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 46% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Synergin gamma	protein	112	46% helix, 2% strand	Q9UMZ2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	147	0.48	0.77	23	empty

Compared structures

2MX7 · Solution structure of the internal EH domain of gamma-synergin · the same entry in another collection · chain A against A, TM-score 1.00
Q9UMZ2 · AlphaFold monomer V2.0 prediction for synergin gamma (Q9UMZ2) · a predicted model of the same protein · chain A against A, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UMZ2
Elsewhere: RCSB PDB 2MX7 · PDBe 2MX7 · UniProt Q9UMZ2

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