MolNFT v1 · #45244 · protein
Structure of the E. COLI threonylcarbamoyl-AMP synthase tsac
2MX1: “Structure of the E. COLI threonylcarbamoyl-AMP synthase tsac”. Solution nmr, 4 pockets (best druggability 0.69). MolNFT v1 #45244 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2MX1
- Type
- protein
- Length
- 189 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Threonylcarbamoyl-AMP synthase
- EC
- 2.7.7.87
- UniProt
- P45748
- Pockets
- 4 · best druggability 0.69
Structure
solution nmr · 1 distinct chain · 32% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Threonylcarbamoyl-AMP synthase (EC 2.7.7.87) | protein | 189 | 32% helix, 15% strand | P45748 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 440 | 0.69 | 0.80 | 60 | empty |
| 2 | 183 | 0.60 | 0.82 | 27 | empty |
| 3 | 226 | 0.59 | 0.80 | 25 | empty |
| 4 | 148 | 0.49 | 0.78 | 32 | empty |
Compared structures
- 2MX1 · Structure of the E. coli Threonylcarbamoyl-AMP Synthase TSAC · the same entry in another collection · chain A against A, TM-score 1.00
- P45748 · AlphaFold monomer V2.0 prediction for threonylcarbamoyl-AMP synthase (P45748) · a predicted model of the same protein · chain A against A, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45748
- Elsewhere: RCSB PDB 2MX1 · PDBe 2MX1 · UniProt P45748
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