MolNFT v1 · #45007 · protein
Solution structure human HCN2 cnbd in the camp-unbound state
2MPF · POTASSIUM/SODIUM hyperpolarization-activated cyclic…: “Solution structure human HCN2 cnbd in the camp-unbound state”. Solution nmr, 1 pocket (best druggability 0.65). MolNFT v1 #45007 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2MPF
- Type
- protein
- Length
- 139 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- POTASSIUM/SODIUM hyperpolarization-activated cyclic nucleotide-gated channel 2
- UniProt
- Q9UL51
- Pockets
- 1 · best druggability 0.65
Structure
solution nmr · 1 distinct chain · 27% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POTASSIUM/SODIUM hyperpolarization-activated cyclic nucleotide-gated channel 2 | protein | 139 | 27% helix, 26% strand | Q9UL51 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 476 | 0.65 | 0.77 | 46 | empty |
Compared structures
- 2MPF · Solution structure human HCN2 CNBD in the cAMP-unbound state · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UL51 · AlphaFold monomer V2.0 prediction for POTASSIUM/SODIUM hyperpolarization-activated cyclic… · a predicted model of the same protein · chain A against A, TM-score 0.73
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UL51
- Elsewhere: RCSB PDB 2MPF · PDBe 2MPF · UniProt Q9UL51
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