MolNFT v1 · #44999 · protein

Solution structure of adf like unc-60A protein of caenorhabditis elegans

2MP4 · Actin-depolymerizing factor 1, isoforms A/B: “Solution structure of adf like unc-60A protein of caenorhabditis elegans”. Solution nmr, 1 pocket (best druggability 0.61). MolNFT v1 #44999 on GenesisL1: 3D structure, binding sites and…

PDB: 2MP4
Type: protein
Length: 165 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Actin-depolymerizing factor 1, isoforms A/B
UniProt: Q07750
Pockets: 1 · best druggability 0.61

Structure

solution nmr · 1 distinct chain · 36% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Actin-depolymerizing factor 1, isoforms A/B	protein	165	36% helix, 25% strand	Q07750

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	183	0.61	0.82	21	empty

Compared structures

2MP4 · Solution Structure of ADF like UNC-60A Protein of Caenorhabditis elegans · the same entry in another collection · chain A against A, TM-score 1.00
Q07750 · AlphaFold monomer V2.0 prediction for actin-depolymerizing factor 1, isoforms A/B (Q07750) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q07750
Elsewhere: RCSB PDB 2MP4 · PDBe 2MP4 · UniProt Q07750

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