MolNFT v1 · #44953 · protein + DNA

The structural basis of DNA binding by the single-stranded DNA-binding protein from sulfolobus solfataricus

2MNA · Ssdna: “The structural basis of DNA binding by the single-stranded DNA-binding protein from sulfolobus solfataricus”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT v1 #44953 on GenesisL1: 3D structure, binding sites and…

PDB: 2MNA
Type: protein + DNA
Length: 123 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ssdna; Single-stranded DNA binding protein (ssb)
UniProt: Q97W73
Pockets: 1 · best druggability 0.31

Structure

solution nmr · 2 distinct chains · 5% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Ssdna	dna	6	—	—
A	Single-stranded DNA binding protein (ssb)	protein	117	5% helix, 34% strand	Q97W73

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.31	0.76	14	empty

Interfaces

1 interface between chains.

B–A · 728 Å² buried · 15 hydrogen bonds · protein-nucleic

Compared structures

2MNA · The structural basis of DNA binding by the single-stranded DNA-binding protein from… · the same entry in another collection · chain B against B, TM-score 1.00
Q97W73 · AlphaFold monomer V2.0 prediction for single-stranded DNA binding protein ssb (Q97W73) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q97W73
Elsewhere: RCSB PDB 2MNA · PDBe 2MNA · UniProt Q97W73

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