MolNFT v1 · #44874 · protein
Solution structure of 6AJL2 and 6AJL2-R24G amyloidogenics light chain proteins
2MKW · V1-22 protein: “Solution structure of 6AJL2 and 6AJL2-R24G amyloidogenics light chain proteins”. Solution nmr, 1 pocket (best druggability 0.35). MolNFT v1 #44874 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2MKW
- Type
- protein
- Length
- 111 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- V1-22 protein
- UniProt
- Q5NV88
- Pockets
- 1 · best druggability 0.35
Structure
solution nmr · 1 distinct chain · 3% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V1-22 protein | protein | 111 | 3% helix, 47% strand | Q5NV88 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.35 | 0.78 | 12 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2MKW · Solution Structure of 6aJl2 and 6aJL2-R24G Amyloidogenics Light Chain Proteins · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5NV88
- Elsewhere: RCSB PDB 2MKW · PDBe 2MKW · UniProt Q5NV88
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