MolNFT v1 · #44689 · protein + RNA
CSR/RSM protein-RNA recognition - a molecular affinity ruler: RSMZ(SL2)/RSME(DIMER) 2:1 complex
2MFE · Carbon storage regulator homolog: “CSR/RSM protein-RNA recognition - a molecular affinity ruler: RSMZ(SL2)/RSME(DIMER) 2:1 complex”. Solution nmr, 2 pockets (best druggability 0.48). MolNFT v1 #44689 on GenesisL1: 3D structure…
- PDB
- 2MFE
- Type
- protein + RNA
- Length
- 162 residues
- Chains
- 4
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbon storage regulator homolog; SL2(RSMZ) RNA
- UniProt
- Q5MXB2
- Pockets
- 2 · best druggability 0.48
Structure
solution nmr · 2 distinct chains · 12% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Carbon storage regulator homolog | protein | 59 | 12% helix, 49% strand | Q5MXB2 |
| B, D | SL2(RSMZ) RNA | rna | 22 | — | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.48 | 0.75 | 22 | empty |
| 2 | 183 | 0.44 | 0.74 | 20 | empty |
Interfaces
5 interfaces between chains.
- A–C · 1929 Ų buried · 37 hydrogen bonds · protein-protein
- A–D · 811 Ų buried · 23 hydrogen bonds · protein-nucleic
- B–C · 767 Ų buried · 22 hydrogen bonds · protein-nucleic
- C–D · 440 Ų buried · 12 hydrogen bonds · protein-nucleic
- A–B · 426 Ų buried · 14 hydrogen bonds · protein-nucleic
Compared structures
- 2MFE · Csr/Rsm protein-RNA recognition - A molecular affinity ruler: RsmZ(SL2)/RsmE(dimer) 2:1… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5MXB2
- Elsewhere: RCSB PDB 2MFE · PDBe 2MFE · UniProt Q5MXB2
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