MolNFT v1 · #44591 · protein

CAT R 1

2MC9 · Peptidyl-prolyl cis-trans isomerase: “CAT R 1”. Solution nmr, 2 pockets (best druggability 0.77). MolNFT v1 #44591 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2MC9
Type: protein
Length: 178 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peptidyl-prolyl cis-trans isomerase
EC: 5.2.1.8
UniProt: Q39613
Pockets: 2 · best druggability 0.77

Structure

solution nmr · 1 distinct chain · 12% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)	protein	178	12% helix, 25% strand	Q39613

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	179	0.77	0.92	36	empty
2	67	0.51	0.85	19	empty

Compared structures

2MC9 · Cat r 1 · the same entry in another collection · chain A against A, TM-score 1.00
Q39613 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase (Q39613) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q39613
Elsewhere: RCSB PDB 2MC9 · PDBe 2MC9 · UniProt Q39613

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